Risk-adjustment in hepatobiliarypancreatic surgery世界胃肠病学杂志：英文版论文
【题名】：Risk-adjustment in hepatobiliarypancreatic surgery世界胃肠病学杂志：英文版论文(Risk-adjustment in hepatobiliarypancreatic surgeryShiJieWeiChangBingXueZaZhi：YingWenBanLunWen) 【关键词】：肝脏手术 胆管手术 胰腺手术 麻醉处理 联合手术 【keywords】：GanZangShouShu DanGuanShouShu YiXianShouShu MaZuiChuLi LianHeShouShu 【作者】：HemantMKocher,ParisPTekkis,PalepuGopal,AmeetGPatel,SimonCottam,IrvingSBenjamin,      【来源】： 知识词典 【期刊名称】：世界胃肠病学杂志：英文版(ShiJieWeiChangBingXueZaZhi：YingWenBan) 【国际标准刊号】：1007-9327        【国内统一刊号】：14-1219 【作者单位】：[1]AcademicDepartmentofSurgery,King＇sCollegeHospital,DenmarkHill,LondonSE59RY,UK [2]DepartmentofAnaesthesia,King＇sCollegeHospital,DenmarkHill,LondonSE59RY,UK([1]AcademicDepartmentofSurgery,King＇sCollegeHospital,DenmarkHill,LondonSE59RY,UK [2]DepartmentofAnaesthesia,King＇sCollegeHospital,DenmarkHill,LondonSE59RY,UK) 【分类号】：R657.3 R657.5      【页码】：-2450-2455      【出版年】：2005.16 【下载地址】：下载pdf全文         AIM: The present study evaluates the performance of the POSSUM, the American Society of Anesthetists (ASA), APACHE and Childs classification in predicting mortality and morbidity in hepatopancreaticobiliary (HPI3) surgery. We describe especially the limitations and advantages of risk in stratifying the patients. METHODS: We investigated 177 randomly chosen patients undergoing elective complex HPB surgery in a single institution with a total of 71 pre-operative and intra-operative risk factors. Primary endpoint was in-hospital mortality and morbidity. Ordered logistic regression analysis was used to identify individual predictors of operative morbidity and mortality. RESULTS: The operative mortality in the sedes was 3.95%. This compared well with the p-POSSUM and APACHE predicted mortality of 4.31% and 4.29% respectively. Postoperative complications amounted to 45% with 24 (13.6%)patients having a major adverse event. On multivariate analysis the pre-operative POSSUM physiological score (OR = 1.18,P = 0.009) was superior in predicting complications compared to the ASA (P = 0.108), APACHE (P = 0.117) or Childs classification (P = 0.136). In addition, serum sodium, creatinine, international normalized ratio (INR), pulse rate, and intra-operative blood loss were independent risk factors. A combination of the POSSUM variables and INR offered the optimal combination of risk factors for risk prognostication in HPB surgery. CONCLUSION: Morbidity for elective HPB surgery can be accurately predicted and applied in everyday surgical practice as an adjunct in the process of informed consent and for effective allocation of resources for intensive and high-dependency care facilities.
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