Pathological study of rabbits＇ femoral arteries subjected to gunshot wounds combining with seawater immersion中华创伤杂志：英文版论文

Pathological study of rabbits＇ femoral arteries subjected to gunshot wounds combining with seawater immersion中华创伤杂志：英文版论文

【题名】：Pathological study of rabbits＇ femoral arteries subjected to gunshot wounds combining with seawater immersion中华创伤杂志：英文版论文(Pathological study of rabbits＇ femoral arteries subjected to gunshot wounds combining with seawater immersionZhongHuaChuangShangZaZhi：YingWenBanLunWen)
【关键词】：病理学兔动物实验股动脉炮伤海水沉浸
【keywords】：BingLiXue Tu DongWuShiYan GuDongMai PaoShang HaiShuiChenJin
【作者】：刘鹏刘晋才赖西南彭学良吴国萍张良潮王丽丽      【来源】：知识词典
【期刊名称】：中华创伤杂志：英文版(ZhongHuaChuangShangZaZhi：YingWenBan)
【国际标准刊号】：1008-1275        【国内统一刊号】：50-1115
【作者单位】：OrthopedicDepartment,ResearchInstituteofFieldSurgery.,DapingHospital,ThirdMilitaryMedicalUniversity,Chongqing400042,China(OrthopedicDepartment,ResearchInstituteofFieldSurgery.,DapingHospital,ThirdMilitaryMedicalUniversity,Chongqing400042,China)
【分类号】：R641      【页码】：-186-190      【出版年】：2005.3
        To investigate pathological characteristics of gunshot wounds concomitant seawater immersion in rabbits' femoral arteries. Methods: Thirty rabbits were divided randomly into 3 groups: simple gunshot-wound group (Group Ⅰ, n = 10), gunshot wound with seawater immersion for 30 mins (Group Ⅱ, n = 10), and 60 mins group (Group Ⅲ, n =10). Femoral arteries were impacted by 0.38 g steel spheres fired with a 7.62 mm rifle. After being wounded, rabbits in Groups Ⅱ and Ⅲ were immersed in seawater for 30 or 60 mins, but those in Group I were not. At 2, 4, 6, 8, 12 hours following injury, a 40 mm segment of the artery on each side of the gunshot point were excised and observed by light and electron microscopy. Results : The potterns of arterial injuries were mainly contusion and transection. Completely transected artery was classified as primary-wound-tract area, contused area and shocked area. Compared with those in Group Ⅰ, the primary-wound-tract and contused areas in Group Ⅱ manifested obvious swelling in the arterial wall especially at the outside 2/3 of the media. Vacuolar structures were often seen in smooth muscle cells of the media. Intercellular space among the smooth muscle cells were filled with homogeneous acidophilic substances. Deep rugae among endothelial cells flattened or rugal folds lost their longitudinal orientation, and marked fibrin and platelet deposition were noticed. No significant difference was detected between Group Ⅱ and Ⅲ. The pathological changes in the shocked area were similar in 3 groups. Conclusions : For gunshot wounds concomitant seawater immersion in rabbits' femoral arteries, there was a marked swelling of cells and intercellular space in primary-wound-tract area and contusion area. The influence of these pathological changes on surgical reparation deservers further study.

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